Coeliac disease: living with intolerance and new approaches to healing
What is coeliac disease?
Coeliac disease is an autoimmune disorder in which the consumption of gluten (a protein found in wheat, barley and rye) leads to inflammation of the small intestine. The intestinal mucosa is damaged by the autoimmune reaction, which can significantly impair the absorption of nutrients. The most common symptoms include
-Chronic digestive disorders (diarrhea, flatulence)
-Weight loss
-fatigue
-Nutrient deficiency
If left untreated, coeliac disease can lead to long-term health problems such as osteoporosis, anemia or neurological disorders.
Cell regeneration as a new treatment approach
Although coeliac disease is currently only treatable with a strict gluten-free diet, there is increasing research pointing to stem cell therapies and regenerative approaches to repair the damaged small intestine. One of the biggest challenges in coeliac disease is the regeneration of the villi in the small intestine, which atrophy as a result of the autoimmune reaction and impair nutrient absorption.
Stem cells have the potential to regenerate intestinal tissue by replacing damaged cells and modulating the immune system. In particular, mesenchymal stem cells (MSCs) show promising results in current studies in the treatment of intestinal damage, as they can reduce inflammation and promote the regeneration of intestinal tissue .
How stem cells could help
1. anti-inflammation
MSCs have a strong anti-inflammatory effect and can modulate the immune response.
2. tissue repair
They promote the regeneration of the small intestine tissue and could support healing in the long term.
3. immune system modulation
By regulating the immune response, the course of the disease in coeliac disease could be positively influenced.
Current studies and progress
Research into the use of stem cell therapies for autoimmune diseases such as coeliac disease shows promising approaches. Studies have already shown that stem cell transplants are able to modulate the immune system so that it acts less aggressively against the patient's own body. For coeliac disease patients, this could mean that the intolerance to gluten could be alleviated or even cured in the long term.
What do the research results say?
-Regenerative therapies
These therapies aim to heal damaged intestinal mucosa and regulate the immune system at the same time.
-Safety and effectiveness
Clinical studies have shown that these approaches are safe for other autoimmune diseases such as ulcerative colitis and Crohn's disease and could also have a potential effect on coeliac disease .
Tips to support the intestines
Although research into regenerative approaches is still in its infancy, coeliac patients can support their gut health through a conscious lifestyle:
-Gluten-free diet
Indispensable to prevent relapses and protect the intestines.
-Nutrient-rich diet
To prevent nutrient deficiencies, coeliac patients should make sure they eat a balanced diet.
-Probiotics and dietary fiber
These can help to strengthen the intestinal flora and support the immune system.
Cell4Care®: Support through cell regeneration
At Cell4Care®, we focus on innovative applications for cell regeneration that can support the gut in chronic diseases such as coeliac disease. By promoting cell healing and modulating the immune system, our therapies can help to sustainably strengthen the gut.
Arrange a free consultation to find out more about how Cell4Care® can support you on your path to better health.
Sources:
1Enhancing regenerative medicine: the crucial role of stem cell therapy
2Stem cells: past, present, and future | Stem Cell Research & Therapy